The strike targeting the capital crashed into the home and injured more than 20 other people, Houthi authorities said.
At least four people have been killed in Sanaa, Yemen, according to the Ministry of Health.
Local sources say Sunday’s attack on the capital hit the home and injured more than 20 other people, including four women and children.
US Warplanes has launched three other airstrikes in the Al Jabal Al Aswad region of Banimatal district, west of the capital. No details regarding casualties were available.
Previously, Houthi’s home base, Saada, and nine people injured, said US airstrikes killed at least two people overnight.
Video broadcast by Houthis’ Al Masirah Satellite News channel showed a strike that collapsed what appeared to be a two-storey building.
The fierce campaign of airstrikes in Yemen under US President Donald Trump has targeted groups lined up in Iran over a Hooty attack on shipments in the Red Sea. The Yemeni group has been attacking in solidarity with the Palestinians during the Israeli war in Gaza.
Dozens of Yemen have been killed in the latest US strike since Trump ordered it to resume last month. Civilians were targeted, families were wiped out, military sites were destroyed, soldiers were killed.
The White House said there have been more than 200 strikes so far.
The US attack began after Houthis said it had planned to resume Israel-linked ships, targeting aid to enter the Gaza Strip and subsequent war reopening, and ended the six-week suspension on March 18.
Houthis targeted more than 100 merchant ships with missiles and drones from November 2023 to January this year.
They also launched attacks targeting US warships.