The storm is part of a tough weather system that cleans the Midwest, leaving behind thousands of people in its power.
At least 21 people have been killed after a tornado caused by a severe storm in Missouri and Kentucky, the officials said.
Kentucky Gov. Andy Besher said on X on Saturday that at least 14 people were killed in the storm on Friday night.
At least seven people were killed in Missouri as authorities began searching for people trapped in the building.
Kentucky officials said they were seriously injured when a tornado tore through Laurel County late Friday. “The search continues in the damaged area for survivors,” Sheriff John Root said in a statement posted on social media.
In Missouri, St. Louis Mayor Carla Spencer confirmed five deaths in her city, saying more than 5,000 homes were affected.
“Our city is in mourning tonight,” she told reporters. “The loss of life and destruction is truly, really, really, horrifying.”
Another tornado struck Scott County, about 209km (130 miles) south of St. Louis, killing two people, wounding several others and destroying multiple homes, Sheriff Derrick Wheatley wrote on social media Friday.
“Our first responders are acting promptly, even while the tornado is still active, and doing harm to the injured in an immediate way to provide support and care,” he said.
The storm that began Friday was part of the harsh weather system that created the tornadoes in Wisconsin, which left thousands of people losing power in the Great Lakes region, resulting in a heat wave that punished Texas.
A Dust Storm warning was issued around the Chicago area Friday night. The Weather Service said a dust wall that stretched along the 161km (100 miles) line from southwest of Chicago to northern Indiana has significantly reduced visibility.
In Texas, heated recommendations have been issued for cities in San Antonio and Austin, with temperatures being issued from the fierce 95f (35c) to 105f (40.5c). Parts of the southeast coast from Virginia to Florida also fought in the heat in the 90s (32-37C).
The National Weather Service offices in Austin and San Antonio said the humidity is expected to be hotter over the weekend.
“People who don’t take appropriate precautions when they’re outdoors have concerns about fever fatigue,” meteorologist Jason Lanien said he advised affected people to stay hydrated and affected.